by Wendy
Submitted by Wendy, Philippines
Hi Dr. Alba,
I am 33 years old, and my doctor told me that my HbA1c is 6.4%. She prescribed metformin hydrochloride 500 mg.
Does this mean that I have diabetes? Can it still be cured? My doctor said that if my HbA1c returns to normal, I may stop the medicine and no longer have diabetes. My father developed diabetes at age 55.
Answer by Dr. Albana Greca, MD, MMedSc
Hi Wendy,
Your HbA1c of 6.4% is in the prediabetes range, not the normal range. It is also very close to the diabetes cutoff, so it deserves confirmation and active follow-up.
Therefore, 6.4% does not meet the usual diabetes threshold, but it is not normal. Our HbA1c guide explains how this test reflects average glucose over roughly the previous three months.
Your clinician may repeat the laboratory HbA1c or use a fasting plasma glucose or two-hour 75-gram oral glucose tolerance test. These tests measure different aspects of glucose metabolism and may not always agree. Our overview of blood tests for diabetes and prediabetes explains their preparation and thresholds.
If HbA1c does not match fasting or after-meal glucose, ask whether anemia, iron deficiency, kidney or liver disease, recent blood loss, or a hemoglobin variant could affect the result.
Metformin is not reserved only for confirmed diabetes. It may be considered to prevent or delay type 2 diabetes in selected high-risk adults, especially those aged 25–59 with HbA1c of 6.0% or higher, higher fasting glucose, severe obesity, or previous gestational diabetes.
You are 33, have HbA1c 6.4%, and have a first-degree relative with diabetes. Your doctor may also have considered your weight, fasting glucose, pregnancy history, cholesterol or blood pressure.
Metformin mainly reduces excess glucose production by the liver and improves insulin sensitivity. Its uses and common side effects are reviewed in our metformin and diabetes medicines guide.
Many people with prediabetes can return their HbA1c or glucose to the normal range and prevent or delay type 2 diabetes. “Cure” is not the best term because the underlying risk can remain, especially with a strong family history.
If you later meet the criteria for type 2 diabetes, improvement without medicine is called remission, not cure. Remission generally means HbA1c below 6.5% for at least three months without glucose-lowering medicine, and continued monitoring is still required.
If you are overweight, losing approximately 5–7% of your starting weight can lower diabetes risk. Aim gradually for at least 150 minutes of moderate activity each week, such as brisk walking, and include resistance exercise when appropriate.
You do not need to run for an hour every day or eat four to five meals. A sustainable plan should emphasize non-starchy vegetables, measured portions of whole fruit, beans, lentils, whole grains, suitable protein and water instead of sugary drinks. Reduce large portions of refined rice, bread, sweets and processed snacks. A practical plan is outlined in our diabetes plate-method guide.
No herb has been proven to normalize HbA1c reliably or prevent diabetes better than established lifestyle treatment. Bitter melon and Gymnema may interact with glucose-lowering medicine. They should not replace metformin or medical follow-up.
People with prediabetes should generally be tested at least yearly, with earlier testing when risk is high or symptoms develop.
HbA1c 6.4% means high-risk prediabetes, not normal glucose and not confirmed diabetes. Repeat the test or complete another accepted laboratory test, continue metformin as prescribed until your doctor reviews the results, and begin realistic lifestyle changes now.
A future normal result would be excellent, but it would not erase your family history or mean that follow-up is no longer needed.
Hope this helps.
Dr. Albana Greca
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