Educational information written by Dr. Albana Greca, MD, Family Physician & General Practitioner,
Medically reviewed by Dr. Ruden Cakani, Endocrinologist
Last reviewed: January 2026
Blood sugar (glucose) levels that are too high or too low can rapidly affect your health. Understanding when your numbers may be dangerous, what symptoms to watch for, and when to act can help prevent serious complications.
This guide explains key ranges, symptoms, and practical next steps you can take.
A blood sugar level becomes dangerous when it is:
Danger is not defined by a number alone. Symptoms, how quickly levels change, illness, medications, and individual health factors all matter.
| Category | mg/dL | mmol/L | Why It’s Concerning |
|---|---|---|---|
| Low blood sugar | <70 | <3.9 | Can impair brain function and increase risk of accidents. |
| Severely low | <54 | <3.0 | High risk of confusion, seizures, or loss of consciousness. |
| High blood sugar | >180 | >10.0 | Ongoing elevation may cause fatigue, thirst, and dehydration. |
| Very high | >240 | >13.3 | Ketone testing recommended, especially during illness. |
| Dangerously high | >300 | >16.7 | Increased risk of DKA or HHS, especially with symptoms. |
| Emergency levels | >600 | >33.3 | Medical emergency — seek urgent hospital care immediately. |
Note: These ranges are for general education. Individual targets vary by age, pregnancy, medications, and medical conditions. If you have vomiting, trouble breathing, confusion, severe weakness, or cannot keep fluids down, seek urgent medical care regardless of the number.
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Low blood sugar becomes dangerous when the brain does not receive enough glucose.
High blood sugar becomes dangerous when it persists or is accompanied by symptoms.
Ketones appear when the body lacks enough insulin and begins breaking down fat for energy.
Moderate or high ketones together with high blood sugar may indicate diabetic ketoacidosis (DKA), a medical emergency.
You should check ketones if:
Positive ketones mean your body is lacking insulin, and urgent medical advice is needed.
Use the 15–15 rule:
Once stable, eat a balanced snack if advised by your healthcare provider.
Never take extra insulin unless it is part of a written correction plan provided by your healthcare provider.
Please seek emergency care right away if:
Is 250 mg/dL dangerous?
This is particularly true if the condition lasts several hours or occurs during an illness. Ketone testing is recommended.
Can blood sugar be dangerous without symptoms?
Yes. Some people feel few symptoms even at very high or low levels, which is why regular monitoring is essential.
Can dangerously high blood sugar be life-threatening?
Yes. Severe hyperglycemia can lead to DKA or HHS, both of which can be fatal without prompt treatment.
Can dangerously low blood sugar be life-threatening?
Yes. Severe hypoglycemia can cause seizures, coma, brain injury, or death if not treated immediately.
Managing blood sugar safely is not about perfection — it is about recognition, timely action, and prevention.
When in doubt, it is always safer to seek medical advice early.
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