by Fre
(Ethiopia)
QUESTION: I am 31 and have type 2 diabetes. I have taken one Daonil tablet each morning for six months, but my fasting glucose is 194 mg/dL and my random after-meal glucose is 204 mg/dL. Why am I not seeing improvement?
Fasting glucose of 194 mg/dL and an after-meal or random reading of 204 mg/dL are above the usual targets for most adults with diabetes. This suggests that the current treatment is not providing adequate control, but you should not increase Daonil yourself. Arrange a prompt medical review for an HbA1c, kidney and liver tests, a medication and meal review, and confirmation that type 2 diabetes is the correct diagnosis.
Answer by Dr. Albana Greca, MD, MMedSc
Hello Fre,
Daonil contains glibenclamide, also called glyburide. It is a sulfonylurea that stimulates the pancreas to release more insulin. Some people respond well, while others need a different dose or additional treatment. Its effect may also become insufficient as type 2 diabetes progresses.
For many nonpregnant adults with diabetes, common individualized goals are 80–130 mg/dL before meals and below 180 mg/dL one to two hours after a meal begins. Your fasting result of 194 mg/dL is clearly above this range, and 204 mg/dL after eating is also elevated.
One or two home readings do not show the full pattern. Record fasting, before-meal, and selected one-to-two-hour after-meal readings in a blood sugar log and bring it to your clinician.
At age 31, especially if you are lean, losing weight, producing ketones, or worsening quickly, your clinician should also consider whether this could be autoimmune diabetes or another diabetes type rather than assuming type 2 diabetes. Our guide to diabetes blood tests explains HbA1c and confirmatory testing.
Ask for an HbA1c, fasting laboratory glucose, kidney function, liver tests, blood pressure, weight, and cholesterol review. Your clinician should confirm the exact Daonil strength, how you take it, whether you experience low glucose, and whether another medicine or insulin is appropriate.
Do not double the tablet or add another diabetes medicine yourself. Glibenclamide can cause prolonged hypoglycemia, particularly when meals are delayed, alcohol is used, or kidney function is reduced. Learn more about sulfonylurea side effects and low-glucose risk.
Continue balanced meals with nonstarchy vegetables, protein, and measured portions of rice, bread, injera, potatoes, or other carbohydrate foods. Avoid sugary drinks and large portions of refined starch. Regular walking can help when you feel well, but lifestyle changes should support—not replace—needed medication adjustment.
Our guide to how foods affect blood sugar can help you compare carbohydrate portions.
A fasting reading of 90 mg/dL is normal, but an after-meal result of 204 mg/dL may still be high. The meaning depends on when it was measured and whether it followed an ordinary meal or a formal oral glucose tolerance test.
If 204 mg/dL was measured one to two hours after an ordinary meal, it is above the common monitoring target and should be discussed with a clinician. If it was a laboratory two-hour result during a 75-gram oral glucose tolerance test, it is within the diabetes diagnostic range. One home after-meal reading alone does not diagnose diabetes; HbA1c and laboratory testing are appropriate.
Seek same-day medical advice if glucose repeatedly reaches 300 mg/dL or higher, especially with excessive thirst, frequent urination, weakness, dehydration, or unexplained weight loss. Go to emergency care for vomiting, abdominal pain, rapid or difficult breathing, fruity-smelling breath, confusion, fainting, high ketones, glucose above 400 mg/dL, or a meter displaying “HI.” Treat glucose below 70 mg/dL promptly.
Six months of fasting glucose near 194 mg/dL should not be managed by continuing the same plan without review. Contact your diabetes clinician soon and bring your medicine package and glucose log. Treatment should be intensified or changed when individualized goals are not met, while also minimizing the hypoglycemia risk from glibenclamide.
Educational safety note: This answer is for general diabetes education only. It does not replace personal medical advice, diagnosis, or treatment. Do not start, stop, or change medicines, supplements, diet, or exercise plans without speaking with your healthcare provider.
Last reviewed: July 2026.
Comments for Fasting Blood Glucose 194, Random BG 204 mg/dL
|
||
|
||
|
||
|
Click here to add your own Comment / Follow up Ask the Doctor now? Simply click here to return to Diabetes Test and Levels. |