Written by Dr.Albana Greca Sejdini, Md, MMedSc
Medically reviewed by Dr.Ruden Cakoni, MD, Endocrinologist
Enzymes for Type 1 Diabetes - Real Remedy or Trick?
QUESTION: Hello people,
I am glad to find such a wonderful site for diabetics... I have type I diabetes for 3 years and interested in reducing insulin doses, because they slowly become higher and higher.
I found many information about enzymes? What do you think about them? Are they worthy or it`s another trick of drug companies?
God bless you guys,
ANSWER: Hi Martin,
Thank you for trusting our loyalty in helping you.
Now, I have tried to gather information regarding these enzymes work.
The new aim of scientists is related to find antigen-specific therapies in type 1 diabetes which is also referred as autoimmune diabetes.
According to recent findings, type 1 diabetes can also be predicted through a simple lab work: measuring the islet auto-antibodies.
The aim is to further understand why the beta cells of the pancreas are being destroyed, what the real mechanism behind this destruction is.
This understanding would further lead to finding the solutions. In other words, finding the real culprit (the real mechanism) and finding the right "weapons" to fight against it/them.
The scientific work is being concentrated into beta-cell antigens, GAD (glutamic acid decarboxylase) and insulin.
These three elements have been suggested to preserve the production of body insulin (i.e. that has being produced endogenously), especially in patients who are newly diagnosed with type 1 diabetes or to prevent it.
Although 12-LO has been revealed as the culprit for type 1 diabetes, the team of physicians at Eastern Virginia Medical School's Strelitz Diabetes Center has failed to give evidence of the efficacity of this enzyme in the humans.
However, the team confirms that this enzyme remains a relevant target in human pancreas, and playing a crucial role in finding new therapies.
At the end, to my opinion, these are all theories and in experimental phase. It is good that researches want to find answers, however, patients must be carefully leaded to the right solutions.
People are becoming more diffident in nowadays. The pharmaceutical companies are the culprit to my opinion. It is good to do business, but not with such high cost: The Human Life!
All the best!