by Debbie Smith
(Upland, ca)
Question from Debbie Smith:
I have had blood sugar readings over 300 mg/dL for more than a month. It was 600 on Saturday. I take Humalog 50/50, 70 units three times a day.
While driving, I had severe pain in my foot near the ankle. By the time I walked into the store, the pain was 9 out of 10 and I could not walk. The foot later improved, but it was still a little swollen, red in areas, and painful with movement.
Could this be a wake-up call that I need better blood sugar control, or is it not related?
Yes, high blood sugar can contribute to leg cramps, foot pain, nerve pain, dehydration, poor circulation, and slow healing. But your symptoms sound more serious than a simple leg cramp.
A blood sugar of 600 mg/dL, repeated readings above 300 mg/dL, and a painful, red, swollen foot need urgent medical evaluation.
This could be related to diabetes, infection, circulation problems, gout, injury, inflammation, Charcot foot, or another foot problem. Please contact your doctor urgently or seek emergency care.
Answer by Dr. Albana Greca, MD, MMedSc
Hi Debbie,
Thank you for sharing your concern. I want to be very clear: blood sugar around 600 mg/dL is very high, especially when you are already using insulin. Together with severe foot pain, swelling, and redness, this should be checked urgently.
Yes. High blood sugar can contribute to leg cramps and pain by causing dehydration, electrolyte changes, nerve irritation, poor circulation, and increased infection risk. Long-term high glucose can also damage nerves, causing burning, tingling, sharp pain, numbness, or cramps in the legs and feet.
Read more here: diabetic nerve pain and diabetes leg pain.
Sudden severe foot or ankle pain with swelling and redness should not be assumed to be only a cramp. In a person with diabetes, possible causes include foot infection, poor blood flow, gout, a small fracture, tendon injury, Charcot foot, neuropathy, or a vascular problem.
Because the pain was severe and you could not walk, you may need a foot exam, pulse check, nerve exam, infection check, blood tests, ketone testing, and possibly an X-ray or other imaging.
Read more here: diabetes and feet.
A reading of 600 mg/dL can lead to severe dehydration and diabetes emergencies, especially if it stays high or comes with infection, vomiting, confusion, weakness, breathing difficulty, or ketones.
Since your glucose has been above 300 mg/dL for more than a month despite insulin, your insulin plan, injection technique, insulin storage, meal plan, and possible infection need urgent review.
Read more here: dangerous blood sugar levels.
Seek emergency help if blood sugar stays very high or you have vomiting, dehydration, confusion, severe weakness, fast or deep breathing, chest pain, fruity-smelling breath, moderate or large ketones, or fever.
Also seek urgent care for a foot that is red, swollen, hot, very painful, numb, blue, black, draining pus, or difficult to walk on.
Debbie, this is a medical warning sign. High blood sugar for a month, a reading of 600 mg/dL, and a painful red swollen foot should be reviewed urgently. Better blood sugar control is important, but the foot also needs examination.
Educational safety note: This answer is for general diabetes education only. It does not replace personal medical advice, diagnosis, or treatment. Do not change insulin or diabetes medication without speaking with your healthcare provider, unless you are following a written correction plan already given to you.
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