Diabetic vitamins and the related scientific data
Diabetic vitamins are amongst the natural remedies that help lowering blood sugar levels. At the same time, they may reduce the bad effects of free radicals and further of kidney and liver damages.In the following paragraphs I will try to explain the importance of vitamins in diabetics through the scientific data.
Diabetic vitamins – Vitamin C
It is also known with the scientific name of ascorbic acid. In one study carried out by a turkish team in Yeditepe University, researchers has concluded that ascorbic acid supplementation has important antagonizing effects on oxidative stress and lipid peroxidation in patients with type 2 diabetes. Taking the polyphenol-rich antioxidant supplement might be beneficial in preventing cardiovascular complications too. Click here to get a Free E-book on “Natural remedies for diabetes”. Ref.: Fenercioglu AK, Saler T, Genc E, Sabuncu H, Altuntas Y. The effects of polyphenol containing antioxidants on oxidative stress and lipid peroxidation in type 2 diabetes mellitus without complications. J Endocrinol Invest. 2009 Oct 15. In another study carried out by a polish team, it has been concluded that impaired glucose is mediated by the poor antioxidation. Ref.: Skalska A, Gasowski J, Grodzicki T. Antioxidants modify the relationship between endothelin-1 level and glucose metabolism-associated parameters. Metabolism. 2009 Sep;58(9):1229-33. Epub 2009 Jun 18. People with diabetes has much more oxidative stress than non-diabetics. What is more, oxidative stress plays an important role in the diabetes complications onset. That's why antioxidant supplements (such as Vitamin C) are beneficial to this category. Ref.: Pan HZ, Zhang L, Guo MY, Sui H, Li H, Wu WH, Qu NQ, Liang MH, Chang D. The oxidative stress status in diabetes mellitus and diabetic nephropathy. Acta Diabetol. 2009 May 28. Diabetic vitamins – Biotin Researchers from South Korea have concluded that biotinylated exendin-4 analogues can be a good oral antidiabetic agent for the treatment of type 2 diabetes. Ref.: Jin CH, Chae SY, Son S, Kim TH, Um KA, Youn YS, Lee S, Lee KC. A new orally available glucagon-like peptide-1 receptor agonist, biotinylated exendin-4, displays improved hypoglycemic effects in db/db mice. J Control Release. 2009 Feb 10;133(3):172-7. Epub 2008 Oct 21 Another study in Japan has concluded that
biotin
could improve the diabetic condition. What is more, biotin may repress the gluconeogenic genes (genes responsible for the production of glucose) and their transcription factors through an insulin-signaling independent pathway. Sugita Y, Shirakawa H, Sugimoto R, Furukawa Y, Komai M. Effect of biotin treatment on hepatic gene expression in streptozotocin-induced diabetic rats. Biosci Biotechnol Biochem. 2008 May;72(5):1290-8. Epub 2008 May 7. Diabetic vitamins –
Vitamin D
Vitamin D is a remarkable multifunctional vitamin which plays important role in varius organs. The following research studies state the role of vitamin D in diabetics. Greek researchers have found that in a homogenous southern European population such as Greece, with low incidence of type 1 diabetes, the polymorphisms of vitamin D receptors gene (various forms of gene) are associated with type 1 diabetes prevalence. Ref.: Panierakis C, Goulielmos G, Mamoulakis D, Petraki E, Papavasiliou E, Galanakis E. Vitamin D receptor gene polymorphisms and susceptibility to type 1 diabetes in Crete, Greece. Clin Immunol. 2009 Nov;133(2):276-81. Epub 2009 Sep 5. McCarty concluded in his research that vitamin D supplements decrease the risk for insulin resistance and obesity. McCarty MF. Poor vitamin D status may contribute to high risk for insulin resistance, obesity, and cardiovascular disease in Asian Indians. Med Hypotheses. 2009 Jun;72(6):647-51. Epub 2009 Feb 12.
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