by Catherine
(Torrance, CA US)
Question: My sister has type 2 diabetes. She did not take her medicine for two days. When she tested at my house, her blood sugar was 415 mg/dL. It scared us both. I do not know when we should take her to the hospital for high blood sugar. Should I have taken her?
Yes. A blood sugar of 415 mg/dL is severely high and warrants urgent same-day medical assessment. Wash and dry the hands and repeat the test with a fresh strip if this can be done immediately, but do not delay emergency care when the person feels ill. If the repeat remains near 415, ketones are moderate or high, serious symptoms are present, or you cannot quickly reach her diabetes clinician, going to the emergency department is appropriate.
Do not double missed tablets or take extra insulin unless she has a written correction plan from her clinician.
Call emergency services now for confusion, unusual drowsiness, fainting, repeated vomiting, severe abdominal pain, deep or difficult breathing, fruity-smelling breath, inability to keep fluids down, severe weakness, chest pain, signs of stroke, or moderate-to-large ketones. Do not let her drive herself.
Missing medicine for two days may contribute to severe hyperglycemia, but it may not be the only cause. Infection, fever, dehydration, steroid medicines, heart attack, stroke, major stress, a change in eating, or worsening insulin deficiency can also raise glucose. A clinician may need to check electrolytes, kidney function, ketones, acid-base status, infection, and whether insulin is temporarily or permanently required.
A glucose of 415 does not mean the blood is “too weak.” It means there is a dangerously high concentration of glucose in the bloodstream. Severe hyperglycemia can cause substantial fluid loss and may progress to diabetic ketoacidosis or hyperosmolar hyperglycemic state.
She should follow the product-specific missed-dose instructions or obtain immediate advice from her prescriber or pharmacist. She should not take two doses together unless a qualified clinician specifically directs this. Some diabetes medicines can cause hypoglycemia when doubled, while others may need to be temporarily withheld during dehydration or acute illness.
If she uses insulin, she should follow her written sick-day and correction plan. People who require basal insulin generally should not omit it, but the exact dose must come from the treating team—not from an online answer.
The previous advice to take the medicine and simply recheck one or two hours later was not sufficiently safe for a reading of 415. Oral medicines are not emergency treatment for diabetic ketoacidosis or severe dehydration. Rechecking is useful, but it should occur while urgent professional advice is being obtained—not as a reason to delay care.
Answered by: Dr. Albana Greca Sejdini, MD, MMedSc
Medically reviewed by: Dr. Ruden Cakoni, MD, Endocrinologist
Last reviewed: July 2026
Medical disclaimer: Educational only—not personal medical advice. Diagnosis and treatment should come from a qualified clinician who knows the patient’s medical history.
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